

Effect of five medicinal plants used in Indian system of medicines on immune function in Wistar rats. Effect of Tribulus terrestris on oxalate metabolism in rats. Phytopharmacological overview of Tribulus terrestris Phcog Rev 2014 8:45-51. Chhatre S, Nesari T, Somani G, Kanchan D, Sathaye S. Antibacterial and antifungal activities of different parts of Tribulus terrestris L. Evaluation of anti-urolithiatic activity of Pashanabhedadi Ghrita against experimentally induced renal calculi in rats. Gupta SK, Baghel MS, Bhuyan C, Ravishankar B, Ashok BK, Patil PD. Studies on the in vitro and in vivo antiurolithic activity of Holarrhena antidysenterica. Investigation of anti-urolithiatic activity of Brassica oleracea gongylodes and Desmostachya bipinnata in experimentally induced urolithiasis in animal models. Kishore RN, Mangilal T, Anjaneyulu N, Abhinayani G, Sravya N. Herbal resources with antiurolithiatic effects: A Review. Evaluation for the anti-urolithiatic activity of Launaea procumbens against ethylene glycol-induced renal calculi in rats.

Makasana A, Ranpariya V, Desai D, Mendpara J, Parekh V. Antiurolithiatic activity of a polyherbal formulation against calcium oxalate induced urolithiasis in rats. Herbal plants used in the treatment of urolithiasis: a review. yadav RD, Alok S, Jain SK, Verma A, Mahor A, Bharti JP et al. Analgesic activity of Calotropis gigantea flower. Anti-urolithiatic activity of Dolichos biflorus seeds. Atodariya U, Barad R, Upadhyay S, Upadhyay U. Antiurolithiatic and antioxidant activity of Mimusops elengi on ethylene glycol-induced urolithiasis in rats. Therefore, the prepared formulation has appreciable significant antiurolithiatic activity and is safe for use.ġ. The level of LD50 was found to be higher than 2000 mg/kg. Histopathology has supported these results. Creatine, uric acid and urea were also decreased significantly at all dose levels. The herbal suspension decreased the level of calcium, oxalate and phosphate significantly at doses of 200 and 300 mg/kg when compared to the negative control group. Ethylene glycol increases the level of calcium, oxalate and phosphate which are responsible for urolithiasis. This formulation contained alcoholic extracts of fruit of Tribulus terrestris, root of Boerhavia diffusa and leaves of Azadirachta indica Studies were performed in ethylene glycol-induced urolithiasis model using Cystone as a standard drug. Hence, herbal formulation containing a mixture of plant extracts was prepared and evaluated for the antiurolithiatic activity. Traditional medicinal plants have been successfully used to overcome urolithiasis. Urolithiasis is the process of formation of stone in the urinary tract by crystal nucleation, aggregation and retention in the urinary tract.
